U.S. FDA-Approved Dermal Fillers

Comoderm and Cosmoplast are U.S. FDA-approved collagen dermal fillers.

Restylane is a hyaluronic acid filler approved by the U.S. FDA in 2004.

Juvederm Ultra and Juvederm Ultra Plus are hyaluronic acid fillers approved by the U.S. FDA in 2006.

Elevess (Anika CTA) is a hyaluronic acid filler with added anesthetic that was approved by the U.S. FDA in 2006.

Perlane is from the Restylane family of hyaluronic acid fillers approved by the U.S. FDA in 2007.

Radiesse was approved by the U.S. FDA in 2006 for cosmetic indications. It is based on calcium microspheres suspended in a gel. The technical name for the microsphere substance in Radiesse is calcium hydroxylapetite, a primary component of teeth and bones.

ArteFill was approved by the U.S. FDA in 2006 as the first non-absorbable dermal filler. It is based on a formulation of 20% synthetic microspheres comprised of PMMA (material used in medical implants) and 80% bovine (cow) collagen with added anesthetic.

Sculptra was approved by the U.S. FDA in 2004 to treat lipoatrophy (loss of facial fat) as the result of HIV (human immunodeficiency virus). It is commonly used off-label in healthy individuals for cosmetic purposes. Sculptra is comprised of poly-L-lactic-acid, a synthetic material similar to that used in absorbable medical sutures.